From jtlightf at uncc.edu Fri Mar 14 15:48:11 2008 From: jtlightf at uncc.edu (Tim Lightfoot) Date: Fri Mar 14 14:50:30 2008 Subject: [CTC] C57L/Js? Message-ID: Hi all: We've been doing some work over the past four years where C57L/Js are an integral part of our research design (we've been working on the genetics of regulation of daily physical activity). While never having an availability issue in the past, over the past 12 weeks, JAX has had extreme difficulty providing us with any C57L/Js at all (they said yesterday that their total inventory at this point are two young males and one young female). Given that we haven't had issues getting them in the past, we had not set up a breeding colony (we are rectifying that! :)). Thus, the following questions: 1) Would anyone have any C57L/Js that they may be willing to part with (of course we'd pay a bit above the going market rate!); and/or 2) Would anyone have any C57L/J brains that they would be willing to part with? Thanks for any help and/or suggestions anyone might have, Tim Lightfoot -- J. Timothy Lightfoot, PhD FACSM RCEP ES Professor Department of Kinesiology UNC Charlotte 9201 University City Blvd. Charlotte, NC 28223 (704) 687-4692 (voice) (704) 687-3350 (fax) "http://www.health.uncc.edu/knes" From arield at cc.huji.ac.il Sun Mar 16 16:37:04 2008 From: arield at cc.huji.ac.il (Ariel Darvasi) Date: Sun Mar 16 09:34:57 2008 Subject: [CTC] case-control DNA samples for SNP-disease association Message-ID: <004501c88773$343b27e0$0200a8c0@ArielHome> To: Members of CTC. You might be interest to know that a new resource is now available at The Hebrew University of Jerusalem. DNA samples from cases and controls in 16 human disease (with 500-1000 cases per disease and a common panel of over 5000 controls) are now accessible to any scientist for testing SNP-disease associations. Among other things this resource allows to test hypotheses originating in mouse studies, directly on humans. For details take a look at www.hugr.org or contact Dr. Michal Bronstein michalbr@savion.huji.ac.il. Best regards, Ariel Darvasi -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mickey.utmem.edu/pipermail/ctc/attachments/20080316/2fb0c0b3/attachment.html From bahlo at wehi.EDU.AU Wed Mar 19 15:11:07 2008 From: bahlo at wehi.EDU.AU (Melanie Bahlo) Date: Tue Mar 18 23:12:08 2008 Subject: [CTC] query re Affy mouse SNP chip Message-ID: <4AE4E78C-C2F6-45A7-805D-D82BABEEDF8E@wehi.edu.au> Hi, Does anyone use the 5K Affy snp chip for mouse mapping? If so, has anyone generated a genetic map? There is no data in the csv annotation file on the Affy website and I have far too few mice to generate a map from scratch. I guess any genetic map would be an interpolation job, or use similar methods that interpolate between physical map positions of the SNP markers to get genetic map positions by using known pairs of physical and genetic map distance, for example those for microsatellite markers. I could do this but I thought I'd ask around first in case anyone had already done this. Thanks, Melanie -------------------------------- Melanie Bahlo Ph.D. NHMRC R. D. Wright Fellow Bioinformatics Division The Walter and Eliza Hall Institute of Medical Research 1G Royal Pde Parkville 3050 VIC Australia bahlo@wehi.edu.au Phone: +613 9345 2630 Fax: +613 9347 0852 http://bioinf.wehi.edu.au/ -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mickey.utmem.edu/pipermail/ctc/attachments/20080319/a16d280f/attachment-0001.html From rwilliam at nb.utmem.edu Thu Mar 27 21:59:07 2008 From: rwilliam at nb.utmem.edu (Rob Williams) Date: Thu Mar 27 22:00:36 2008 Subject: [CTC] KO: genes affected by the environment Message-ID: <7DC14779-7D7D-4C72-9F11-F0069BCDC626@nb.utmem.edu> To: CTC Members Please nominate NOMINATE up to 10 genes affected by the environment that you feel should have priority for being knocked out in the KOMP (Knockout Mouse Project) http://www.informatics.jax.org/mgihome/KOMP/nominationForm.shtml . Requests can be made for conditional and/or simple null mutations. All knockouts are currently being done in a C57BL/6N background. In your request, please check off the GEI box if the gene is affected by the environment. Jonathan D. Pollock, Ph.D Chief Genetics and Molecular Neurobiology Research Branch Division of Basic Neuroscience and Behavioral Research 6001 Executive Blvd Bethesda, MD 20892 tel. 301-435-1309 fax. 301-594-6043 email. jpollock@mail.nih.gov Rob Robert W. Williams, Ph.D. Professor, Department of Anatomy and Neurobiology Dunavant Chair, Department of Pediatrics University of Tennessee Health Science Center 855 Monroe Avenue Memphis TN 38163 rwilliam@nb.utmem.edu or labwilliams@gmail.com tell: 901 448-7050 -------------- next part -------------- An HTML attachment was scrubbed... URL: http://mickey.utmem.edu/pipermail/ctc/attachments/20080327/e2aed50d/attachment.html From mkotb at utmem.edu Fri Mar 28 02:15:33 2008 From: mkotb at utmem.edu (malak kotb) Date: Fri Mar 28 02:17:22 2008 Subject: [CTC] KO: genes affected by the environment In-Reply-To: <7DC14779-7D7D-4C72-9F11-F0069BCDC626@nb.utmem.edu> References: <7DC14779-7D7D-4C72-9F11-F0069BCDC626@nb.utmem.edu> Message-ID: Il1, Ptges, Ptges2, all TLRs, heat shock 70KDa protein 5 (Hspa5) and all NLR genes all cytokines, chemokines, chemokine receptors and MAT-II? On 3/27/08, Rob Williams wrote: > > To: CTC Members > > Please nominate NOMINATE up to 10 genes affected by the environment that you > feel should have priority for being knocked out in the KOMP (Knockout Mouse > Project) http://www.informatics.jax.org/mgihome/KOMP/nominationForm.shtml. > Requests can be made for conditional and/or simple null mutations. All > knockouts are currently being done in a C57BL/6N background. In your > request, please check off the GEI box if the gene is affected by the > environment. > > Jonathan D. Pollock, Ph.D > Chief > Genetics and Molecular Neurobiology Research Branch > Division of Basic Neuroscience and Behavioral Research > 6001 Executive Blvd > Bethesda, MD 20892 > tel. 301-435-1309 > fax. 301-594-6043 > email. jpollock@mail.nih.gov > > > Rob > > Robert W. Williams, Ph.D. > Professor, Department of Anatomy and Neurobiology > Dunavant Chair, Department of Pediatrics > University of Tennessee Health Science Center > 855 Monroe Avenue > Memphis TN 38163 > rwilliam@nb.utmem.edu > or labwilliams@gmail.com > tell: 901 448-7050 > > > > > > _______________________________________________ > CTC mailing list > CTC@mickey.utmem.edu > http://mickey.utmem.edu/mailman/listinfo/ctc > >